• 24 Hr. Age Defying Cream

Le Mieux

24 Hr. Age Defying Cream

(11 reviews) Write a Review

Rich, creamy formula with multiple forms of hyaluronic acid fortifies the skin's essential moisture barrier, reduces the appearance of fine lines and wrinkles, and helps promote firmness, resiliency, and lasting hydration for up to 24 hours. Skin-refining peptides, ceramides, and cupuacu, shea, and kukui butters help soothe dryness and irritation. Highly effective for improving the appearance of crepey, weathered neck skin as well as unsightly stretch marks. Ideal for mature skin.

MIX & MATCH Any 6 Retail Moisturizers* and receive FREE Cryo Peptide Eye Masks (pro size) March 23 - April 3, 2026. SHOP NOW.

*Excludes Platinum Pro Collection, PurErb, and Kizo Lab

 

Use morning and night following cleansing. Gently apply onto face and neck in an upward and outward motion.

Galactomyces Ferment Filtrate, Sodium Hyaluronate, Oryza Sativa (Rice) Bran Water, Hyaluronic Acid, Zinc Hydrolyzed Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Dimethylsilanol, Sodium Hyaluronate Crosspolymer, C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Ascorbyl Propyl Hyaluronate, Palmitoyl Tripeptide-5, Theobroma Grandiflorum Seed Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Squalane, Pyrus Malus (Apple) Fruit Water, Phospholipids, Acetyl Hexapeptide-8, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Acetyl Glutamine, Acetyl Octapeptide-3, DNA, Sodium Carboxymethyl Beta-Glucan, Dipalmitoyl Hydroxyproline, Ceramide EOP, Ceramide NP, Palmitoyl Pentapeptide-4, Vitis Vinifera (Grape) Seed Oil, Butyrospermum Parkii (Shea) Butter, Aleurites Moluccana Seed Oil, Oryza Sativa (Rice) Bran Oil,  Enteromorpha Compressa Extract, Morus Alba Root Extract, Saccharomyces Lysate Extract, Tocotrienols, Camellia Sinensis Extract, Vitis Vinifera (Grape) Seed Extract, Vaccinium Myrtillus Seed Extract, Sphingomonas Ferment Extract, Tocopherol, Caprylyl Glycol, Ethylhexylglycerin, Undecylenoyl Glycine, Capryloyl Glycine.

Rich, creamy formula with multiple forms of hyaluronic acid fortifies the skin's essential moisture barrier, reduces the appearance of fine lines and wrinkles, and helps promote firmness, resiliency, and lasting hydration for up to 24 hours. Skin-refining peptides, ceramides, and cupuacu, shea, and kukui butters help soothe dryness and irritation. Highly effective for improving the appearance of crepey, weathered neck skin as well as unsightly stretch marks. Ideal for mature skin.

MIX & MATCH Any 6 Retail Moisturizers* and receive FREE Cryo Peptide Eye Masks (pro size) March 23 - April 3, 2026. SHOP NOW.

*Excludes Platinum Pro Collection, PurErb, and Kizo Lab

 

Use morning and night following cleansing. Gently apply onto face and neck in an upward and outward motion.

Galactomyces Ferment Filtrate, Sodium Hyaluronate, Oryza Sativa (Rice) Bran Water, Hyaluronic Acid, Zinc Hydrolyzed Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Dimethylsilanol, Sodium Hyaluronate Crosspolymer, C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Ascorbyl Propyl Hyaluronate, Palmitoyl Tripeptide-5, Theobroma Grandiflorum Seed Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Squalane, Pyrus Malus (Apple) Fruit Water, Phospholipids, Acetyl Hexapeptide-8, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Acetyl Glutamine, Acetyl Octapeptide-3, DNA, Sodium Carboxymethyl Beta-Glucan, Dipalmitoyl Hydroxyproline, Ceramide EOP, Ceramide NP, Palmitoyl Pentapeptide-4, Vitis Vinifera (Grape) Seed Oil, Butyrospermum Parkii (Shea) Butter, Aleurites Moluccana Seed Oil, Oryza Sativa (Rice) Bran Oil,  Enteromorpha Compressa Extract, Morus Alba Root Extract, Saccharomyces Lysate Extract, Tocotrienols, Camellia Sinensis Extract, Vitis Vinifera (Grape) Seed Extract, Vaccinium Myrtillus Seed Extract, Sphingomonas Ferment Extract, Tocopherol, Caprylyl Glycol, Ethylhexylglycerin, Undecylenoyl Glycine, Capryloyl Glycine.

11 Reviews

5 / 5
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  • 5 / 5
    Amazing

    Posted by marina clough on 24th Sep 2025

    My clients love it

  • 4 / 5
    Great Night Cream for me

    Posted by Laura B. on 18th Jun 2025

    This cream on my skin type (dehydrated) is a tad too heavy to wear during the day, but a wonderful cream to use in my nighttime routine. Thank you Le Mieux

  • 5 / 5
    Age defying-yes

    Posted by Lori on 15th Dec 2024

    I try new products all the time and come back to 24 hour age defying moisturizer every time. It’s a bit thicker consistency but it absorbs completely . Nothing compares to this moisturizer.

  • 5 / 5
    24 hour Age Defying Cream

    Posted by Christine Sheridan on 13th Sep 2023

    I absolutely love this product. I have mature skin and this really helped my wrinkles look less noticeable. Very Happy!

  • 5 / 5
    24 hr night cream

    Posted by Ryle holmes Relume Esthetics on 7th Jun 2023

    This is the perfect night cream! It is heavier, for more dry skin or dehydrated skin you could use this during the day.

  • 5 / 5
    None better than these ingredients

    Posted by Belle Tuckerman on 24th Feb 2023

    Multiple forms of HA, peptides, ceramides and skin softening nut butter oils, this creme gets a 5 star rating from me. In my 42 years as a medically trained esthetician I have never seen results in my patients like I have with the LeMieux system. It works.